COVID-19: guidance for sampling and for diagnostic laboratories

Last updated 29 March 2021
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Updated samples required for initial diagnostic testing (section 3).
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Updated section 2 and 3 of ‘laboratory investigations and sample requirements for diagnosis’.
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Updated section 3 of ‘laboratory investigations and sample requirements for diagnosis’.
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Updated link to video on packaging diagnostic samples containing Hazard group 3 (HG3) pathogens.
Addition of link to reinstated E28 primary testing form. -
Updated ‘COVID-19: sampling and packaging poster’.
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Update on sample submission to ‘laboratory investigations and sample requirements for diagnosis’ page.
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Updated ‘COVID-19: safe handling and processing for samples in laboratories’.
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Note on urine testing added to the ‘safe handling and processing for samples’ page.
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Updated with latest information on the infectivity of human specimens with SARS-CoV-2 virus (section 2) with key references.
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Added clarification that this guidance refers to how hospital-based healthcare workers can arrange laboratory testing for patients and inclusion of a link to essential workers testing guidance.
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New version of the diagnostic sample video added.
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Updated upper respiratory tract sample options; added ‘guidance on alternative swab types and transport media’; replaced posters for samples to take and packaging instructions.
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Updated information on local testing.
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Updated information on how to arrange local laboratory testing.
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Additional guidance on processing samples regarding near patient testing.
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Updated information on samples and testing.
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‘Priority for testing’ moved to ‘investigation and initial clinical management of possible cases’.
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Added links to ‘Packaging and transport requirements for patient samples – UN3373’.
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Added ‘Packaging requirements for COVID-19 samples’, and updated the sample packaging poster.
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Clarification on work to be conducted at CL3.
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Added Priority of SARS-CoV-2 (COVID-19) testing during periods of significant demand.
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Updated guidance ‘COVID-19: safe handling and processing for samples in laboratories’.
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Added reference to MERS testing in the laboratory investigation page, and updated the ‘how to arrange testing’ page.
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Update to list of laboratories in the ‘how to arrange laboratory testing’ document.
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Updated list of laboratories in the ‘how to arrange laboratory testing’ document.
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Update to designated laboratories.
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Revisions to safe handling and processing for laboratories, and added video describing sample packaging.
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Updated guidance for laboratory investigations and sample requirements.
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Update to guidance on how to arrange testing.
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Updated information on packaging and transport of samples.
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Updated posters and text editions.
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Updated information on process for sending samples to PHE.
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Clarification to ‘who to call to request testing’.
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Added clarification of sampling and packaging, with new and revised posters.
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Added information about biosafety levels.
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Update to risk assessment and point of care tests.
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Added laboratory specimen and packing requirements and poster.
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Added who to call to request laboratory testing document.
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Added ‘Laboratory investigations and sample requirements’ document and algorithm.
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First published.
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